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These final results, together with a preceding report displaying that a small-molecule ACKR3 agonist CCX771 displays anxiolytic-like behavior in mice,2 assist the principle of concentrating on ACKR3 as a singular method to modulate the opioid system, which could open up new therapeutic avenues f

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In a very modern study, we documented the identification as well as the characterization of a fresh atypical opioid receptor with exceptional destructive regulatory Houses toward opioid peptides.1 Our success showed that ACKR3/CXCR7, hitherto referred to as an atypical scavenger receptor for che